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Product Details:
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| Name: | Sunitinib Malate | Cas: | 341031-54-7 |
|---|---|---|---|
| Mf: | C22h27fn4o2.C4h6o5 | Content: | 99% |
| Appearance: | White Powder | Package: | 5kgs/bottle |
| Quality Standard: | CP,USP | ||
| High Light: | API Sunitinib Malate,CAS 341031-54-7 Sunitinib Malate,99% Purity Sunitinib Malate |
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China API supplier Sunitinib Malate / Sunitinib API / CAS 341031-54-7
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Product Name
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Sunitinib Malate |
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Appearance
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Pale yellow to off-white powder |
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Assay
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99%min, 98.0% --101.0% |
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Test
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HPLC
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Certificate
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ISO 9001
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CAS
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341031-54-7 |
| MF | C22H27FN4O2.C4H6O5 |
| Storage Temperature |
Cool Dry Place
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What is Sunitinib Malate ?Sunitiba Malate is an antineoplastic agent and a potent RTK inhibitor which includes Flk-1 (VEGFR2) as a primary target. It also is a potent, ATP-competitive inhibitor of VEGFR, PDGFR-β and c-Kit (KIT). Sunitiba Malate inhibits cellular receptor phosphorylation of FLT3, RET and CSF-1R. Exhibits antiangiogenic and antitumor activity in multiple xenograft models. Sunitinib Malate is an inhibitor of c-Fms-CSF-1R, Flt-1, Flt-3/Flk-2, Flt-4, PDGFR-α and Ret. |
Sunitinib Malate has very good oral bioavailability, is highly efficacious
in a number of preclinical tumor models, and is well tolerated at efficacious doses.
Sunitinib malate is an inhibitor used in the treatment of advanced renal cell carcinoma
and gastrointestinal stromal tumors.
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