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| Name: | Naftopidil | Appearance: | White Powder |
|---|---|---|---|
| CAS: | 57149-07-2 | Package: | Aluminum Foil Bag |
| Production Capacity: | 500 Kilogram/month | Storage: | Kept In A Cool,dry And Ventilated Place |
| Purity: | 99% | MF: | C24H28N2O3 |
| High Light: | Naftopidil Pharma Intermediates,CAS 57149-07-2 Pharma Intermediates,C24H28N2O3 Pharma Intermediates |
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High Quality Naftopidil Good Effect Naftopidil Powder Naftopidil Dihydrochloride CAS: 57149-07-2
| Chemical Name | Naftopidil dihydrochloride |
|---|---|
| Synonyms | Avishot;Naftopiil;Flivas;NAFTOPIDIL;Naftopidildihydrochloride;Expand |
| CAS No. | 57149-07-2 |
| Molecular Formula | C24H28N2O3 |
| Molecular Weight | 392.49100 |
| PSA | 45.17000 |
| LogP | 3.41320 |
Product Details:
Product name: Naftopidil dihydrochloride
MF: C24H28N2O3
MW: 392.49
CAS: 57149-07-2
Purity: 99%+
Product Specifications: Pharmacopoeial Grade
Brand: Biocar
Origion: Hebei, China
Export Markets: Global
Application:
Naftopidil for the treatment of dysuria associated with benign prostatic hypertrophy (BPH). It can be prepared by a two step route starting with α-naphthol. Naftopidil is a potent postsynaptic-selective alpha-l-antagonist with a slightly higher affinity for the human prostatic than for the aortic alpha-adrenoceptor. It also shows a 5-HT1A agonistic effect, as well as a weak calcium antagonistic activity, but no alpha-2 or beta-adrenoreceptor affinity. In experiments with rats or rabbits, Naftopidil was shown to be more potent and selective for the urodynamic effect than the hypotensive effect. Aromatic or aliphatic hydroxylation are the major routes of metabolism, producing metabolites with a profile similar to the parent compound.
Chemical PropertiesOff-White Solid
UsesA α-1-Adrenergic receptor antagonist, antihypertensive.
Usesantihypertensive, alpha-blocker, 5HT1a agonist
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