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Naftopidil Pharma Intermediates Naftopidil Dihydrochloride CAS: 57149-07-2

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Naftopidil Pharma Intermediates Naftopidil Dihydrochloride CAS: 57149-07-2

Naftopidil Pharma Intermediates Naftopidil Dihydrochloride CAS: 57149-07-2
Naftopidil Pharma Intermediates Naftopidil Dihydrochloride CAS: 57149-07-2

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Product Details:
Place of Origin: China
Brand Name: germax
Certification: GMP
Model Number: Naftopidil
Payment & Shipping Terms:
Minimum Order Quantity: 100 gram
Price: Negotiable
Packaging Details: 1kg/bag or 25kgs/drum
Delivery Time: within 24 hours after get the payment
Payment Terms: Western Union, MoneyGram, T/T
Supply Ability: 500KG/week
Detailed Product Description
Name: Naftopidil Appearance: White Powder
CAS: 57149-07-2 Package: Aluminum Foil Bag
Production Capacity: 500 Kilogram/month Storage: Kept In A Cool,dry And Ventilated Place
Purity: 99% MF: C24H28N2O3
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Naftopidil Pharma Intermediates


CAS 57149-07-2 Pharma Intermediates


C24H28N2O3 Pharma Intermediates

High Quality Naftopidil Good Effect Naftopidil Powder Naftopidil Dihydrochloride CAS: 57149-07-2



Chemical Name Naftopidil dihydrochloride
Synonyms Avishot;Naftopiil;Flivas;NAFTOPIDIL;Naftopidildihydrochloride;Expand
CAS No. 57149-07-2
Molecular Formula C24H28N2O3
Molecular Weight 392.49100
PSA 45.17000
LogP 3.41320


Product Details:

Product name: Naftopidil dihydrochloride
MF: C24H28N2O3
MW: 392.49
CAS: 57149-07-2
Purity: 99%+
Product Specifications: Pharmacopoeial Grade
Brand: Biocar
Origion: Hebei, China
Export Markets: Global


Naftopidil for the treatment of dysuria associated with benign prostatic hypertrophy (BPH). It can be prepared by a two step route starting with α-naphthol. Naftopidil is a potent postsynaptic-selective alpha-l-antagonist with a slightly higher affinity for the human prostatic than for the aortic alpha-adrenoceptor. It also shows a 5-HT1A agonistic effect, as well as a weak calcium antagonistic activity, but no alpha-2 or beta-adrenoreceptor affinity. In experiments with rats or rabbits, Naftopidil was shown to be more potent and selective for the urodynamic effect than the hypotensive effect. Aromatic or aliphatic hydroxylation are the major routes of metabolism, producing metabolites with a profile similar to the parent compound.
Chemical PropertiesOff-White Solid
UsesA α-1-Adrenergic receptor antagonist, antihypertensive.
Usesantihypertensive, alpha-blocker, 5HT1a agonist



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