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|CAS:||144701-48-4||Package:||Aluminum Foil Bag|
|Production Capacity:||500 Kilogram/month||Storage:||Kept In A Cool,dry And Ventilated Place|
Telmisartan Pharma Intermediates,
144701-48-4 Pharma Intermediates,
C33H30N4O2 Pharma Intermediates
Telmisartan CAS144701-48-4 Telmisartan Good Quality Telmisartan Low Price 99% Raw Materials Telmisartan
|Application||Pharma grade or research purpose|
|Packing||As per your request|
|Storage||Preserve in tight, light-resistant containers in a cool place|
Telmisartan, 4'-[(1,4'-dimethyl-2'-propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl]-[1,1'-biphenyl]-2-carboxylic acid (Micardis), does not appear to bear any structuralrelationship to this class, but there is actually a great dealof overlap in the chemical architecture with other agents.
The first, and most significant, difference is the replacement of the acidic tetrazole system with a simple carboxylic acid. This acid, like the tetrazole, plays a role in receptor binding.
The second difference is the lack of a carboxylic acid near the imidazolenitrogen that also contributes to receptor binding.As with irbesartan, however, there is not a need for this groupto be acidic but, rather, to be one that participates in receptorbinding. The second ring, much like a purine basein deoxyribonucleic acid (DNA), can hydrogen bond with theangiotensin II receptor.
Used alone or in combination with other classes of antihypertensives for the treatment of hypertension. Also used in the treatment of diabetic nephropathy in hypertensive patients with type 2 diabetes mellitus.
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