Payment & Shipping Terms:
|Product Name:||Ambroxol HCl||Purity:||99%|
|Min Order:||1kg||Production Capacity:||5000 Kilogram/week|
|Deliver Day:||Within 48 Hours After Get The Payment|
CAS 15942-05-9 fine Chemicals,
C17h14brn3o2s white powder
Ambroxol HCl CAS 15942-05-9 Ambroxol Hydrochloride C17h14brn3o2s
Ambroxol hydrochloride is a kind of grume dissolving agent developed by the Boehringer Ingelheim Company (Germany), and had first entered into market in Germany in the early 1980s. It has been subsequently approved for entering into France, Italy, Japan, Spain and many other countries.
As a new generation of sputum dissolving agent, it can improve the expectoration, and has effect on promoting the secretion of the lung surfactant and airway as well as the ciliary movement.Clinically it can be used for adjusting the secretion of grume and pulp, activation of swing of the ciliary. It can make it easy for sputum dissolution, strengthen the outward transport of sputum and make it easy for being discharged. It can also promote the biosynthesis of lung surfactant and maintain the tension of the alveoli and the functional parameter of the lung function; promote the antibiotics to penetrate through the tissues, increase their concentrations and enhance the bactericidal effect; it has antioxidant effect and can reduce the release of inflammatory mediators and reduce the inflammation reaction; it also has synergistic effect with bronchial spasmolysis and improve the efficacy of the antispasmodic drugs.
Ambroxol hydrochloride has a significant antioxidant effect and can have a significant effect on the reactivity of the free oxygen radicals associated with the lung disease lesions. Studies have shown that ambroxol has strong inhibitory effect on the H2O2 produced by the neutrophils; in addition, ambroxol can also activate the intracellular glutathione system, promote the biosynthesis of the intracellular glutathione (GSH), thereby causing damaging effects on the oxygen free radicals. It can be used as cough medicine,and used as antitussive and expectorant drugs, for acute and chronic respiratory diseases, especially chronic bronchitis expectorant treatment. Can promote the discharge of viscous secretions within the respiratory tract and reduce the retention of mucus, which significantly promote sputum. It is suitable for acute and chronic respiratory diseases accompanied by abnormal sputum secretion and expectoration dysfunction.
|Appearance||White or yellowish crystalline powder|
First Identification: BD
A.UV absorption 3.2-3.4ratioB. IR spectrum
C. Thin layer chromotography
D. Chlorides test
|Solubility||Sparingly soluble in water, soluble in methanol,practically insoluble in Methylene chloride|
|Appearance of solution||Clear and not more intensely colored than the reference solution Y6|
|Loss on drying||≤0.5%|
|Residue on ignition||≤0.1%|
|Related substances||Specified impurities
|Assay(on dried basis)||99.0-101.0%|
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