99% Favipiravir CAS 259793-96-9 Specification

Favipiravir is an antiviral drug. Favipiravir, also known as T705, or Avigan, is a selective inhibitor of viral RNA-dependent RNA polymerase with activity against many RNA viruses, influenza viruses, West Nile virus, yellow fever virus, foot-and-mouth disease virus as well as other flaviviruses, arenaviruses, bunyaviruses and alphaviruses. Activity against enteroviruses and Rift Valley fever virus has also been demonstrated. The mechanism of its actions is thought to be related to the selective inhibition of viral RNA-dependent RNA polymerase. Favipiravir does not inhibit RNA or DNA synthesis in mammalian cells and is not toxic to them. In 2014, favipiravir was approved in Japan for stockpiling against influenza pandemics.

 

 

99% Favipiravir CAS 259793-96-9 Application & Function

 

99% Favipiravir CAS 259793-96-9 Function
Favipiravir is a nucleoside antiviral drug, the mechanism of action has not been fully explained. The target is the viral rna-dependent RNA polymerase. After oral absorption, the drug was converted into a bioactive nucleoside triphosphate of Favipiravir, whose structure was similar to that of purine Chemicalbook and could compete with purines for viral RNA polymerase.
The nucleoside triphosphates of Favipiravir can also be inserted into viral RNA strands, inducing lethal mutations in the virus.
Therefore, in terms of mechanism, Favipiravir has potential antiviral effect on various RNA viruses

99% Favipiravir CAS 259793-96-9 Application

Favipiravir can be used for antiviral treatment of influenza a and b. Research shows that, in addition to influenza virus, the drug also showed good antiviral activity against a variety of RNA viruses, such as ebola virus, sand virus, bunya virus, rabies virus..