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Apixaban Pharma Ingredients CAS 503612-47-3 For Anticoagulants

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Apixaban Pharma Ingredients CAS 503612-47-3 For Anticoagulants

Apixaban Pharma Ingredients CAS 503612-47-3 For Anticoagulants
Apixaban Pharma Ingredients CAS 503612-47-3 For Anticoagulants

Large Image :  Apixaban Pharma Ingredients CAS 503612-47-3 For Anticoagulants Get Best Price

Product Details:
Place of Origin: China
Brand Name: germax
Certification: GMP
Model Number: Apixaban
Payment & Shipping Terms:
Minimum Order Quantity: 1kg
Price: Negotiable
Packaging Details: 1kg/bag or 25kgs/drum
Delivery Time: within 3 days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 500kgs/week
Detailed Product Description
Name: Apixaban Cas: 503612-47-3
Mf: C25H25N5O4 Purity: 99%
Appearance: White Powder Package: 1kg/bag Or 25kgs/drum
High Light:

Apixaban Pharma Ingredients

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503612-47-3 Apixaban

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Anticoagulants Pharma Ingredients

Top Quality 99% Raw Powder Apixaban CAS 503612-47-3 for Anticoagulants Apixaban Powder

 

Product name: Apixaban
Other name: Eliquis
Appearance: White Powder
CAS NO.: 503612-47-3
M.F.: C25H25N5O4
M.W.:459.497
Grade: Pharmaceutical grade

Apixaban is an orally active inhibitor of coagulation factor Xa with anticoagulant activity. Apixaban directly inhibits factor Xa, thereby interfering with the conversion of prothrombin to thrombin and preventing formation of cross-linked fibrin clots.

 

 

Apixaban is the third new oral anticoagulant to go on sale, following dabigatran and rivaroxaban, and it has already been approved in Europe for preventing venous thromboembolism in patients undergoing elective hip or knee replacement surgery. Out of these three oral anticoagulants approved in Europe, compared to the current standard preventative treatment against venous thromboembolism, enoxaparin, rivaroxaban excelled in the record experiment, and apixaban excelled in the advance experiment. Rivaroxaban's curative effects were slightly superior, but it caused more severe bleeding than apixaban. Researchers attributed these differences to medication time, as rivaroxaban was taken 6-8 hours after surgery in the record experiment, while apixaban was used 18 hours after surgery in the advance experiment. These drugs have better curative effect when used closer to time of surgery, but also have an increased bleeding risk. Clinical research showed that compared to a daily subdermal injection of 40mg enoxaparin, 2 oral 2.5mg dosages of apixaban had better preventative effects against venous thromboembolism following hip or knee replacement surgery and did not increase bleeding risk.

 

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