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GMP Pharmaceutical Candesartan Cilexetil CAS 145040-37-5

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Very happy to work with this company , they did their part ensure quick delivery, if you need something domestic don't go anywhere else ,great friendly people to do great business with

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GMP Pharmaceutical Candesartan Cilexetil CAS 145040-37-5

GMP Pharmaceutical Candesartan Cilexetil CAS 145040-37-5
GMP Pharmaceutical Candesartan Cilexetil CAS 145040-37-5

Large Image :  GMP Pharmaceutical Candesartan Cilexetil CAS 145040-37-5 Get Best Price

Product Details:
Place of Origin: China
Brand Name: germax
Model Number: Raw Steroid Powder
Payment & Shipping Terms:
Minimum Order Quantity: 1kg
Price: Negotiable
Packaging Details: 1kg/bag or 25kgs/drum
Delivery Time: within 3 days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 2000kgs/month
Detailed Product Description
Name: Candesartan Cilexetil CAS: 145040-37-5
Purity: 99.5% Appearance: White Powder
Packing: 1kg/Bag,10kg/Drum,25kg/Drum Or As Required MF: C33H34N6O6
MOQ: 1KG
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Pharmaceutical Candesartan Cilexetil

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GMP Candesartan Cilexetil

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CAS 145040-37-5

Best quality GMP manufacturing pharmaceutical Candesartan Cilexetil CAS 145040-37-5

 

 
CAS No. 145040-37-5
Molecular Formula C33H34N6O6
LogP 6.3191
PSA 143.34
Density 1.37 g/cm3
Boiling point 843.3ºC at 760 mmHg
Solubility Soluble in DMSO, not in water
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Stock Solution Storage 0 - 4 C for short term (days to weeks), or -20 C for long term (months)

 

Product Name: Candesartan Cilexetil
Chemical Name: 2-ethoxy-3-[4-[2-(2H-tetrazol-5-yl)phenyl]benzyl]benzimidazole-4-carboxylic acid 1-(cyclohexoxycarbonyloxy)ethyl ester
CAS NO.: 145040-37-5
Molecular Formula:C33H34N6O6
Formula Weight: 610.66
Properties:
Appearance: Off-white crystalline powder.
Density: 1.37 g/cm3
Boiling point: 843.3ºC at 760 mmHg
Flash point: 463.8 ºC
Refractive index: 1.665

 


Candesartan cilexetil is a prodrug of the potent, long-acting, and selective angiotensin II type 1 receptor (AT1) antagonist, candesartan. It is rapidly hydrolyzed to candesartan during gastrointestinal absorptio. Candesartan blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II by selectively blocking the binding of angiotensin II to the AT1 receptor in many tissues, such as vascular smooth muscle and the adrenal gland. Its action is, therefore, independent of the pathways for angiotensin II synthesis. Candesartan has much greater affinity ( > 10,000-fold) for the AT1 receptor than for the AT2 receptor.

 

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