Payment & Shipping Terms:
|Packing:||1kg/Bag,10kg/Drum,25kg/Drum Or As Required||MF:||C20H22N8O5|
CAS 59-05-2 Pharmaceutical Chemicals,
Methotrexate Pharmaceutical Chemicals,
MTX Pharmaceutical Chemicals
Pharmaceuticals Chemical Methotrexate Powder Supplier and Manufacturer with CAS 59-05-2 Exporter
|Product name||99.9% High quality Methotrexate CAS No. 59-05-2 Anti-Cancer|
|Place of origin||China|
Methotrexate (MTX) Description:
Methotrexate (MTX), formerly known as amethopterin, is a chemotherapy agent and immune system suppressant.It is used to treat cancer, autoimmune diseases, ectopic pregnancy, and for medical abortions. Types of cancers it is used for include breast cancer, leukemia, lung cancer, lymphoma, and osteosarcoma. Types of autoimmune diseases it is used for include psoriasis, rheumatoid arthritis, and Crohn's disease. It can be given by mouth or by injection.
Methotrexate interferes with the growth of certain cells of the body, especially cells that reproduce quickly, such as cancer cells, bone marrow cells, and skin cells. Methotrexate is used to treat certain types of cancer of the breast, skin, head and neck, or lung. It is also used to treat severe psoriasis and rheumatoid arthritis. Methotrexate is usually given after other medications have been tried without successful treatment of symptoms. Methotrexate may also be used for purposes not listed in this medication guide.
Methotrexate (MTX) Application
Methotrexate (MTX), formerly known as amethopterin, is a chemotherapy agent and immune system suppressant. It is used to treat cancer, autoimmune diseases, ectopic pregnancy, and for medical abortions. Types of cancers it is used for include breast cancer, leukemia, lung cancer, lymphoma, and osteosarcoma. Types of autoimmune diseases it is used for include psoriasis, rheumatoid arthritis, and Crohn's disease. It can be given by mouth or by injection.
Methotrexate is used as a disease-modifying treatment for some autoimmune diseases, including rheumatoid arthritis, juvenile dermatomyositis, psoriasis, psoriatic arthritis, lupus, sarcoidosis, Crohn's disease (although a recent review has raised the point that it is fairly underused in Crohn's disease), eczema and many forms of vasculitis. Although originally designed as a chemotherapy drug (using high doses), in low doses, methotrexate is a generally safe and well tolerated drug in the treatment of certain autoimmune diseases. Because of its effectiveness, low-dose methotrexate is now first-line therapy for the treatment of rheumatoid arthritis. Weekly doses are beneficial for 12 to 52 weeks duration therapy, although discontinuation rates are as high as 16% due to adverse effects. Although methotrexate for autoimmune diseases is taken in lower doses than it is for cancer, side effects such as hair loss, nausea, headaches, and skin pigmentation are still common. Use of low doses of methotrexate together with NSAIDS such as aspirin or paracetamol is relatively safe in people being treated for rheumatoid arthritis, if adequate monitoring is done.
|Standard adopted||USP 30|
|Items of analysis||Specification||Results|
|Description||Orange or yellow crystalline powder||Conforms|
|Identification||IR , UV||Conforms|
|Water||Not more than 12.0%||9.7%|
|Residue on ignition||Not more than 0.1%||0.06%|
|Chromatographic purity||Total: Not more than 2.0%||0.81 %|
|Chromatographic purity||Individual: Not more than 0.5%||0.24%|
|Specific rotation||Between +19°and +24°||+22.5°|
|Organic volatile impurities||Ethanol: not more than 0.5%||0.35%|
|Organic volatile impurities||Aether : not more than 0.5%||0.19%|
|Assay||Between 98.0% and 102.0%||99.55%|
|Solubility||practically insoluble in water,chloroform,ethanol and ether, freely soluble in watery alkali, soluble in watery hydrochloric acid.||Conforms|
Packaging & Shipping&Payment
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