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| Name: | Calcitonin Salmon | Cas: | 47931-85-1 |
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| MF: | C145H240N44O48S2 | Purity: | 99% |
| Appearance: | White Powder | Package: | 1kg/bag Or 25kgs/drum |
| High Light: | Postmenopause Osteoporosis Calcitonin Salmon,47931-85-1 Calcitonin Salmon,99% Purity Calcitonin Salmon |
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Factory Fast Delivery Postmenopause Osteoporosis Calcitonin Salmon Raw Powder CAS 47931-85-1
Description:
What is Calcitonin Salmon?
Calcitonin (salmon) is an hypocalcemic hormone produced by the parafollicular C cells of the thyroid or by the ultimobranchial bodies of nonmammalian vertebrates. Calcitonin decreases blood calcium and phosphate due to inhibition of resorption by osteoblasts and osteocytes. Calcitonin contains a single disulfide bond, which causes the amino terminus to assume the shape of a ring. Alternative splicing of the calcitonin pre-mRNA can yield a mRNA encoding calcitonin gene-related peptide; that peptide appears to function in the nervous and vascular systems. The calcitonin receptor has been cloned and shown to be a member of the seven-transmembrane, G protein-coupled receptor family.
Application:
-Treatment of postmenopausal women with osteoporosis at high risk for fracture
-Increase of bone mass in men with primary or hypogonadal osteoporosis at high risk for fracture
-Treatment of men and women with osteoporosis associated with sustained systemic glucocorticoid therapy at high risk for fracture
| Item | Standard | Test Results |
| Identification | A.H-NMR:Comply with the structure | Complies |
| B.LC-MS:Comply with the structure | Complies | |
| C.The IR spectrum of sample should be identical with that of reference standard; | Complies | |
| D.HPLC-ESI-MS The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay. |
Complies | |
| Crystallinity | meets the requirements. | Complies |
| Loss on drying | ≤2.0% | 0.19% |
| Heavy metals | ≤10 ppm | <10ppm |
| Water | ≤1.0% | 0.1% |
| Sulphated ash | ≤0.5%, determined on 1.0 g. | 0.009% |
| Related substances | Unspecified impurities: for each impurity | <0.10% |
| Total Impurity | 0.18% | |
| Purity | ≥99.0% | 99.7% |
| Assay | 99.0%~101.0% (anhydrous substance). | 99.8% |
| Microbiological Analysis | ||
| Total plate count | ≤1000cfu/g | Complies |
| Yeast and Moulds | ≤100cfu/g | Complies |
| E. Coli. | Absent | Negative |
| Salmonella | Absent | Negative |
| S.aureus | Absent | Negative |
| Storage | Preserve in well-closed, light-resistant and airtight containers. | Complies |
Contact Person: July
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