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White Crystalline CAS 53123-88-9 Rapamycin Powder

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Very happy to work with this company , they did their part ensure quick delivery, if you need something domestic don't go anywhere else ,great friendly people to do great business with

—— Jim Frank

Excellent quality and customer service , shipped fast with no delay other than extensive inspection here in the U.S . But not at fault of the supplier , the product is professionally packaged and i will definitely be looking forward to continued cooperation .

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Our order was 100% pure after lab testing with quick delivery and professional service .Will order again .

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This is a very good product .I will order more in the future , it got here U.S quickly , thanks . Dan

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White Crystalline CAS 53123-88-9 Rapamycin Powder

Name: White Crystalline CAS 53123-88-9 Rapamycin Powder
Brand: germax
SKU: Rapamycin
Price: 1.00 USD
Availability: InStock
Rating: 5 (121 reviews)

Large Image : White Crystalline CAS 53123-88-9 Rapamycin Powder Get Best Price

Product Details:

Place of Origin:	China
Brand Name:	germax
Model Number:	Rapamycin

Payment & Shipping Terms:

Minimum Order Quantity:	10 gram
Price:	Negotiable
Packaging Details:	10g/bottle ,50g/bottle , 100g/bag ,1kg/bag
Delivery Time:	within 3 days
Payment Terms:	T/T, Western Union, MoneyGram
Supply Ability:	2000 grams/month

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Detailed Product Description

Name:	Rapamycin	CAS:	53123-88-9
Purity:	99.5%	MF:	C51H79NO13
Appearance:	White Powder	Packing:	1kg/Bag,10kg/Drum,25kg/Drum Or As Required
High Light:	CAS 53123-88-9 Rapamycin Powder , White Crystalline Rapamycin Powder , Sirolimus Rapamycin Powder

Raw Pharmaceutical Grade Material Sirolimus CAS 53123-88-9 Powder Rapamycin

Product Name	Rapamycin
CAS	53123-88-9
Appearance	White Crystalline Powder
Molecular formula	C51H79NO13
Molecular Weight	914.18
Assay	99.5%
Shelf Life	24 months when properly stored
Storage	Keep in a cool, dry, dark location

What is Rapamycin?

Rapamycin is a member of the macrolide immunosuppressant family and a FRAP inhibitor.

Rapamycin exhibits binding and inhibitory actions to the FK506 binding protein (FKBP5) proline rotamase via simultaneous binding by FKBP12 and FRAP. FRAP (RAFT1) proteins exhibit homology to PI 4- and PI 3-kinases,which have PI 4-kinase and autophosphorylating activities.

The rapamycin/FKBP complex does not inhibit the FRAP PI 4-kinase activity,but does inhibit FRAP autophosphorylation.

Rapamycin is unique in its ability to inhibit lymphokine induced cell proliferation at the G1 and S phase as well as an irreversible cellular arrest at the G1 phase in S. cerevisiae cells.

Rapamycin also exhibits selective signal blocking leading to the activation of p70/85 S6 kinase, which is
potentially due to the inhibition of FRAP autophosphorylation or protein kinase activity. Angiogenesis inhibition is also exhibited,possibly through the inhibition of the Akt pathway.

Rapamycin is an inhibitor of mTOR.

Function And Application of Rapamycin

Rapamycin is a triene macrolide antibiotic,which demonstrates anti-fungal,anti-inflammatory,anti-tumor and immunosuppressive properties.

Rapamycin has been shown to block T-cell activation and proliferation,as well as,the activation of p70 S6 kinase and exhibits strong binding to FK506 binding proteins.

Rapamycin also inhibits the activity of the protein,mTOR(mammalian target of rapamycin) which functions in a signaling pathway to promote tumor growth.

Rapamycin binds to a receptor protein (FKBP12) and the rapamycin/FKB12 complex then binds to mTOR and prevents interaction of mTOR with target proteins in this signaling pathway.

Rapamycin (RAPA) is a novel macrolide immunosuppressant is now often used as a transplanted organ to maintain immunity drugs (especially kidney transplants), to mitigate the immune organ rejection after transplant surgery, but scientists it recently found another purpose: for the treatment of Alzheimer's disease (senile dementia).

Target of rapamycin (mTOR) as an intracellular kinases pathway abnormalities can induce a variety of diseases. As rapamycin mTOR inhibitor targeting, to treat with this pathway is closely related to tumors, including renal cell carcinoma, lymphoma, lung cancer, liver cancer, breast cancer, neuroendocrine carcinoma and gastric cancer

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