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Name: | Benzocaine | CAS: | 94-09-7 |
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Form: | White Crystalline Powder | Content: | 99% |
Min Order: | 1Kg | Molecular Formula: | C9h11no2 |
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Supply high quality Pharmaceutical cas 94-09-7 benzocaine
Product name:benzocaine
Appearance:white crystalline powder
CAS:94-09-7
MF:C9H11NO2
MW:165.189
EINECS:202-303-5
Colorless or white rhombic crystalline powder. No odor, slightly bitter taste, after the sense of anesthesia. Change color in the light. Insoluble in water, slightly soluble in fat oil, soluble in dilute acid, ethanol, ether, chloroform, almond oil, olive oil.Used as a local anesthetic. Long - term effect, low toxicity. It is mainly used for relieving pain of skin diseases, trauma, hemorrhoids and ulcer. Some condom companies add benzocaine to condoms to slow men's ejaculation during sex.
Test Items | Specification | Test Results |
Appearance | White crystals or a white crystalline powder | Conform |
Identification | ABE. It appears positive reaction | |
Melting point | 154degree~158degree | 154degree~157degree |
Acidity | PH 5.0~6.5 | PH=5.9 |
Appearance of solution | Clear and colourless | Conform |
Loss on drying | ≤0.5% | 0.07% |
Heavy metals | ≤0.0005% | Conform |
Related substances | ≤0.05% | Conform |
Sulphated ash | ≤0.1% | 0.05% |
Assay ( on dry basis ) | 99.0-101.0% | 99.87% |
Conclusion | Conform to BP200 |
Application
Medical uses:
Benzocaine is indicated to treat a variety of pain-related conditions. It may be used for:
Local anesthesia of oral and pharyngeal mucous membranes (sore throat, cold sores, mouth ulcers, toothache, sore gums, denture irritation)
Otic pain (earache)
Surgical or procedural local anesthesia.
Benzocaine is used as a key ingredient in numerous pharmaceuticals:
Some glycerol-based ear medications for use in removing excess wax as well as relieving ear conditions such as otitis media and swimmers ear.
Some previous diet products such as Ayds.
Some condoms designed to prevent premature ejaculation. Benzocaine largely inhibits sensitivity on the penis, and can allow for an erection to be maintained longer (in a continuous act) by delaying ejaculation. Conversely, an erection will also fade faster if stimulus is interrupted.
Benzocaine mucoadhesive patches have been used in reducing orthodontic pain.
In Poland it is included, together with menthol and zinc oxide, in the liquid powder (not to be confused with the liquid face powder) used mainly after mosquito bites. Today's ready made Pudroderm was once used there as pharmaceutical compound.
Pain is caused by the stimulation of free nerve endings. When the nerve endings are stimulated, sodium enters the neuron, causing depolarization of the nerve and subsequent initiation of an action potential. The action potential is propagated down the nerve toward the central nervous system, which interprets this as pain. Benzocaine acts to inhibit the voltage-dependent sodium channels (VDSCs) on the neuron membrane, stopping the propagation of the action potential.
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