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High Purity Powder Rapamycin Raw Powder Sirolimus 99%Min CAS 53123-88-9 Chemical Research

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Very happy to work with this company , they did their part ensure quick delivery, if you need something domestic don't go anywhere else ,great friendly people to do great business with

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Excellent quality and customer service , shipped fast with no delay other than extensive inspection here in the U.S . But not at fault of the supplier , the product is professionally packaged and i will definitely be looking forward to continued cooperation .

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Our order was 100% pure after lab testing with quick delivery and professional service .Will order again .

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This is a very good product .I will order more in the future , it got here U.S quickly , thanks . Dan

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High Purity Powder Rapamycin Raw Powder Sirolimus 99%Min CAS 53123-88-9 Chemical Research

High Purity Powder Rapamycin  Raw Powder Sirolimus 99%Min CAS 53123-88-9 Chemical Research
High Purity Powder Rapamycin  Raw Powder Sirolimus 99%Min CAS 53123-88-9 Chemical Research

Large Image :  High Purity Powder Rapamycin Raw Powder Sirolimus 99%Min CAS 53123-88-9 Chemical Research Get Best Price

Product Details:
Place of Origin: China
Brand Name: germax
Certification: GMP
Model Number: Rapamycin
Payment & Shipping Terms:
Minimum Order Quantity: 1kg
Price: Negotiable
Packaging Details: 1kg/bag or 25kgs/drum
Delivery Time: within 3 days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 500kgs/week
Detailed Product Description
Name: Sirolimus Cas: 53123-88-9
Mf: C51H79NO13 Purity: 99%
Appearance: White Powder Package: 1kg/bag Or 25kgs/drum
High Light:

Rapamycin Raw Powder

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53123-88-9 Sirolimus Raw Powder

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Rapamycin Chemical Research

High Purity Powder Rapamycin Raw Powder Sirolimus 99%Min CAS 53123-88-9 Chemical Research

 

Detailed Product Information

Product Name: Rapamycin
Brand Name: Rapamune
CAS No.: 53123-88-9
Molecular Formula: C51H79NO13
Molecular Weight: 914.19g/mol
Purity : 99%
Appearance: White Crystalline Powder
Typical use:Novel immunosuppressants
Standard Packing : 1gram,10gram,100gram
Shelf Life :2 years
Storage:Room temperature away from light
 

Description:

What is Rapamycin?
Rapamycin (Sirolimus) slows aging, extends life span, and prevents age-related diseases, including diabetic complications such as retinopathy. Puzzlingly, rapamycin can induce insuli sensitivity, but may also induce insuli resistance or glucose intolerance without insuli resistance. This mirrors the effect of fasting and very low calorie diets, which improve insuli sensitivity and reverse type 2 diabetes, but also can cause a form of glucose intolerance known as benevolent pseudo-diabetes. There is no indication that starvation (benevolent) pseudo-diabetes is detrimental. By contrast, it is associated with better health and life extension. In transplant patients, a weak association between rapamycin/everolimus use and hyperglycemia is mostly due to a drug interaction with calcineurin inhibitors. When it occurs in cancer patients, the hyperglycemia is mild and reversible. No hyperglycemic effects of rapamycin/everolimus have been detected in healthy people. For antiaging purposes, rapamycin/everolimus can be administrated intermittently (e.g., once a week) in combination with intermittent carbohydrate restriction, physical exercise, and metformin.

Rapamycin (known clinically as Sirolimus or Rapamune) and its analog, RAD001 (everolimus), are FDA-approved drugs widely used in humans. Rapamycin, a natural product, is older, cheaper, better studied, and more available than everolimus, though everolimus is increasingly being used clinically. Both drugs inhibit mTOR complex 1 (mTORC1) by the same mechanism, and their biological effects are identical at equipotent concentrations, taking into account that rapamycin is slightly more potent and has a longer half-life than everolimus1. Although the difference in their pharmacokinetics within the human body has been well characterized, that difference has not yet been exploited for clinical purposes, and neither drug is considered superior to the other. As a result, studies with these two drugs complement one another: what has been shown for rapamycin is largely applicable to everolimus and vice versa (at equivalent concentrations). We will use the term rapalogs to encompass both drugs rather than everolimus alone.


Typical Properties:

Novel immunosuppressants


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