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Macitentan Api Active Pharmaceutical Ingredient CAS 441798-33-0

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Macitentan Api Active Pharmaceutical Ingredient CAS 441798-33-0

Macitentan Api Active Pharmaceutical Ingredient CAS 441798-33-0
Macitentan Api Active Pharmaceutical Ingredient CAS 441798-33-0

Large Image :  Macitentan Api Active Pharmaceutical Ingredient CAS 441798-33-0 Get Best Price

Product Details:
Place of Origin: China
Brand Name: germax
Certification: GMP
Model Number: Macitentan
Payment & Shipping Terms:
Minimum Order Quantity: 1kg
Price: Negotiable
Packaging Details: 1kg/bag or 25kgs/drum
Delivery Time: within 3 days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 500kgs/week
Detailed Product Description
Name: Macitentan Cas: 441798-33-0
Mf: C19H22Br2N6O4S Purity: 99%
Appearance: White Powder Package: 1kg/bag Or 25kgs/drum
High Light:

Macitentan Active Pharmaceutical Ingredient

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CAS 441798-33-0 Macitentan

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API 99% Macitentan

API Macitentan Powder CAS 441798-33-0 Macitentan Raw Material CAS 441798-33-0 Macitentan Powder

 

 

Product Name macitentan
Synonyms N-[5-(4-Bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)-oxy]ethoxy]-4-pyrimidinyl]-N'-propylsulfami;macitentan;N-[5-(4-Bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinyl]-N'-propylsulfamide;ACT 064992;ACT-064992;ACT-064992 / ACT064992;SulfaMide,N-[5-(4-broMophenyl)-6-[2-[(5-broMo-2-pyriMidinyl)oxy]ethoxy]-4-pyriMidinyl]-N'-propyl-;N-[5-(4-Bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinyl]-N'-propylsulfamide Macitentan
CAS 441798-33-0
MF C19H22Br2N6O4S
MW 590.295
EINECS 1308068-626-2

 

Macitentan is an endothelin receptor antagonist (ERA) approved for the treatment of pulmonary arterial hypertension (PAH). The other two ERAs marketed as of 2014 are bosentan and ambrisentan. Macitentan is a dual ERA, meaning that it acts as an antagonist of two endothelin (ET) receptor subtypes, ETA and ETB. However, macitentan has a 50-fold increased selectivity for the ETA subtype compared to the ETB subtype.

 

 

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