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Panobinostat Pharmaceutical Intermediates CAS 404950-80-7

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Panobinostat Pharmaceutical Intermediates CAS 404950-80-7

Panobinostat Pharmaceutical Intermediates CAS 404950-80-7
Panobinostat Pharmaceutical Intermediates CAS 404950-80-7

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Product Details:
Place of Origin: China
Brand Name: germax
Certification: GMP
Model Number: Panobinostat
Payment & Shipping Terms:
Minimum Order Quantity: 1kg
Price: Negotiable
Packaging Details: 1kg/bag or 25kgs/drum
Delivery Time: within 3 days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 500kgs/week
Detailed Product Description
Name: Panobinostat Cas: 404950-80-7
Mf: C21H23N3O2 Purity: 99%
Appearance: White Powder Package: 1kg/bag Or 25kgs/drum
High Light:

Panobinostat Pharmaceutical Intermediates


404950-80-7 Panobinostat


C21H23N3O2 Panobinostat

High Quality Panobinostat Powder CAS 404950-80-7 Pharmaceutical Intermediate Panobinostat CAS 404950-80-7 


Product name Panobinostat
CAS No. 404950-80-7
Molecular formula C21H23N3O2
Molecular weight 349.43
Purity 99%
Appearance White or almost white powder
Package Aluminum Bag;Drums
Shelf life  2 years


Panobinostat is a cinnamic hydroxamic acid analogue with potential antineoplastic activity. Panobinostat selectively inhibits histone deacetylase (HDAC), inducing hyperacetylation of core histone proteins, which may result in modulation of cell cycle protein expression, cell cycle arrest in the G2/M phase and apoptosis. In addition, this agent appears to modulate the expression of angiogenesis-related genes, such as hypoxia-inducible factor-1alpha (HIF-1a) and vascular endothelial growth factor (V EGF), thus impairing endothelial cell chemotaxis and invasion. HDAC is an enzyme that deacetylates chromatin histone proteins.



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