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|CAS:||72559-06-9||Package:||Aluminum Foil Bag|
|Production Capacity:||500 Kilogram/month||Storage:||Kept In A Cool,dry And Ventilated Place|
Rifabutine Chemical Raw Materials,
CAS 72559-06-9 Chemical Raw Materials,
Rifabutin Mycobutin Chemical Raw Materials
Rifabutine CAS 72559-06-9 Ansatipine Mycobutin Medical High Quality Rifabutin Mycobutin for Anti-Tuberculosis
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Product Name: Rifabutin
Synonyms: 4-Deoxw3,4-[2-spiro(N-isobutyl-4-pipendyl)]-(1H)-imidazo-(2,5-dihydro)rifamycin S;4-N-ISOBUTYLSPIROPIPERIDYLRIFAMYCIN S;RIFABUTIN;RIFABUTINE;1,4-dihydro-1-deoxy-1',4-didehydro-5'-(2-methylpropyl)-1-oxo-rifamycinxi;(9S,12E,14S,15R,16S,17R,18R,19R,20S,21S,22E,24Z)-6,16,18,20-Tetrahydroxy-1'-isobutyl-14-methoxy-7,9,15,17,19,21,25-hepta-methyl-spiro[9,4-(epoxypentadeca[1,11,13]trienimino)-2H-furo-[2',3':7,8]-naphth[1,2-d]imidazol-2,4'-piperidin]-5,10,26-(3H,9H)-trione;Ansatipine;Mycobutin
Melting point: 169-171°C
Boiling point: 329.1±15.0 °C
Density: 1.137±0.06 g/cm3
Storage temp.: Amber Vial, -20°C Freezer, Under Inert Atmosphere
Appearance: Red-Brown Powder
Rifabutin, a rifamycin antibacterial derivative, is the first agent approved and introduced for the prevention of Mycobacterium avium complex (MAC) in AIDS patients. It is also indicated in combination chemotherapy for the prophylaxis and treatment of MAC infections in HIV positive patients and for newly diagnosed and chronic tuberculosis.
Rifamycins are antibiotics that inhibit DNA-dependent RNA polymerases and are usually bactericidal against Gram-positive bacteria but bacteriostatic against Gram-negative bacteria. Rifamycins are also effective against Mycobacterium species, including M. tuberculosis. Rifabutin is a broad-spectrum rifamycin antibiotic that has applications against tuberculosis, H. pylori, M. avium complex, Chlamydia, and other bacteria. It is also useful in co-infections with human immunodeficiency virus, including tuberculosis.
It is a spiral-piperidine derivative of rifamycin, and its inhibitory effect on Mycobacterium tuberculosis is about 4 times stronger than that of rifamycin. Mainly used for divergent bacilli pulmonary infection, effective for rifampicin resistant tuberculosis bacilli strains, can be used for drug resistance, relapse tuberculosis cases, intracellular divergent bacilli infection and the treatment of AIDS.
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