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Product Details:
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Name: | Adefovir Dipivoxil | Appearance: | White Powder |
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CAS: | 142340-99-6 | Package: | Aluminum Foil Bag |
Production Capacity: | 500 Kilogram/month | Storage: | Kept In A Cool,dry And Ventilated Place |
Purity: | 99% | MF: | C20H32N5O8P |
High Light: | High Purity Adefovir Dipivoxil,142340-99-6 Pharmaceutical Chemical,C20H32N5O8P Pharmaceutical Chemical |
99% High Purity Adefovir Dipivoxil CAS 142340-99-6 Pharmaceutical Chemical Powder
Introduction:
Adefovir dipivoxil is an oral broad-spectrum antiviral drug that can inhibit the activity of HBV DNA polymerase, and can penetrate into the DNA of hepatitis B virus, inhibit virus replication, and is resistant to lamivudine and famciclovir. , Has a strong inhibitory effect, and is clinically used in the treatment of hepatitis.
Product Name | Adefovir dipivoxil |
CAS | 142340-99-6 |
EINECS | 200-001-8 |
Assay | 99% |
MF | C20H32N5O8P |
MW | 501.47 |
Appearance | White Powder |
Usage | Adefovir dipivoxil has a broad spectrum of antiviral activity, can be used for the treatment of chronic hepatitis B. |
Description:
Adefovir is an orally active prodrug that is indicated for thetreatment of the chronic form of hepatitis B. The dipivoxil moieties are hydrolyzed by ubiquitous esterases to yieldadefovir, which is phosphorylated by adenylate kinase toyield adefovir diphosphate. This compound is inhibitory atHBV DNA polymerase. In addition, adefovir undergoes incorporationinto viral DNA and causes chain termination.Adefovir is poorly absorbed by the oral route, but the dipivoxilester groups cause the bioavailability to increase toapproximately 60%.
Usage:
Has a broad spectrum of antiviral activity, can be used for the treatment of chronic hepatitis B.
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