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White Powder Purity 99% Palonosetron Hydrochloride CAS 135755-51-0

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Very happy to work with this company , they did their part ensure quick delivery, if you need something domestic don't go anywhere else ,great friendly people to do great business with

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Excellent quality and customer service , shipped fast with no delay other than extensive inspection here in the U.S . But not at fault of the supplier , the product is professionally packaged and i will definitely be looking forward to continued cooperation .

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This is a very good product .I will order more in the future , it got here U.S quickly , thanks . Dan

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White Powder Purity 99% Palonosetron Hydrochloride CAS 135755-51-0

White Powder Purity 99% Palonosetron Hydrochloride CAS 135755-51-0
White Powder Purity 99% Palonosetron Hydrochloride CAS 135755-51-0

Large Image :  White Powder Purity 99% Palonosetron Hydrochloride CAS 135755-51-0 Get Best Price

Product Details:
Place of Origin: China
Brand Name: germax
Certification: GMP
Model Number: Palonosetron Hydrochloride
Payment & Shipping Terms:
Minimum Order Quantity: 1kg
Price: Negotiable
Packaging Details: 1kg/bag or 25kgs/drum
Delivery Time: within 3 days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 500kgs/week
Detailed Product Description
Name: Palonosetron Hydrochloride Cas: 135755-51-0
Mf: C19H24N2O.HCl Purity: 99%
Appearance: White Powder Package: 1kg/bag Or 25kgs/drum
High Light:

Palonosetron Hydrochloride


135755-51-0 Palonosetron Hydrochloride


White Powder Palonosetron Hydrochloride

Big Discount Purity 99% Palonosetron Hydrochloride CAS 135755-51-0 with Best Quality



Product Name: Palonosetron Hydrochloride
Synonyms: (S)-2-((S)-quinuclidin-3-yl)-2,3,3a,4,5;Palonosetron hydrochloride, 99.5%, a 5-HT3 antagonist;PALONOSETRON HCL;PALONOSETRON HYDROCHLORIDE;CS-292;Palonosetronhydrochloride hydrochloride;Palonosetron-d3 HCl;(3aS)-2-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-1H-benz[de]isoquinolin-1-one Hydrochloride
CAS: 135729-62-3
MF: C19H25ClN2O
MW: 332.87
EINECS: 680-630-6
Melting point: >290°C
Storage temp.: Refrigerator


Palonosetron hydrochloride is a drug to inhibit nausea and vomiting, which is a new type highly selective, high-affinity 5-HT3 receptor antagonist that can block the vomiting reflex center peripheral neurons presynaptic 5-HT. Receptor excitement directly affects the central nervous system in 5-HT. Impulse receptor excitement generated by the role of vagal afferent nerve after area, blocking the vagus nerve endings in the gut, preventing signals to 5-HT. Receptor trigger zone can reduce the incidence of nausea and vomiting. Central clinically for the treatment of acute severe emetogenic chemotherapy induced delayed nausea and vomiting. Because of its high curative effect, little side effect, long half-life (about 40 h), small dosage, and so on, it has attracted much attention.


Serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.


Batch No. HF210420 Quantity 2.2kgs
Mfg. Date Apr. 20, 2021 Package As required
Rep. Date Apr. 23, 2021 Exp. Date Apr. 19, 2023
Items Standards Results
Appearance White or off-white crystalline powder Complies
Identification By IR Complies
By HPLC Complies
Solubility Freely soluble in water, soluble in methanol and 0.1mol/L hydrochloric acid solution,hardly soluble in isopropyl alcohol Complies
Clarity&Color of Solution Clear and Colourless Complies
Specific Rotation -93°~-103° -94.4°
R,R-Isomer 0.02% ND
pH 4.5~6.0 5.69
Sulfate 0.06% Complies
Chloride(on dried basis) 9.6%~11.7% 10.7%
Loss on Drying 0.50% 0.10%
Heavy Metals 10ppm Complies
Residue on Ignition 0.10% 0.06%
Residual Solvents Methanol: 3000ppm ND
Ethanol: 5000ppm 600
Diethyl ether: 5000ppm ND
Tetrahydrofuran: 720ppm ND
Ethyl acetate: 5000ppm ND
Isopropanol: 5000ppm ND
Chloroform: 60ppm ND
Toluene: 890ppm ND
N,N-Dimethylformamide: 880ppm ND
Related Substances Diastereomer: 0.10% 0.003%
Nitrogen oxides: 0.10% 0.006%
Other individual impurity: 0.10% ND
Total Impurities: 0.50% 0.01%
Assay (on the anhydrous basis) 99.0%~101.0% 99.46%
Reference Standard In-house Standard
Conclusion The product complied to In-house standard.
Storage Preserve in tight, light-resistant containers in a cool place






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