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C25h28n8o2 Linagliptin Active Pharmaceutical Ingredient CAS 668270-12-0

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Excellent quality and customer service , shipped fast with no delay other than extensive inspection here in the U.S . But not at fault of the supplier , the product is professionally packaged and i will definitely be looking forward to continued cooperation .

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This is a very good product .I will order more in the future , it got here U.S quickly , thanks . Dan

—— Dan Bedrock

C25h28n8o2 Linagliptin Active Pharmaceutical Ingredient CAS 668270-12-0

C25h28n8o2 Linagliptin Active Pharmaceutical Ingredient CAS 668270-12-0
C25h28n8o2 Linagliptin Active Pharmaceutical Ingredient CAS 668270-12-0

Large Image :  C25h28n8o2 Linagliptin Active Pharmaceutical Ingredient CAS 668270-12-0 Get Best Price

Product Details:
Place of Origin: China
Brand Name: germax
Certification: GMP
Model Number: Linagliptin
Payment & Shipping Terms:
Minimum Order Quantity: 1kg
Price: Negotiable
Packaging Details: 1kg/bag or 25kgs/drum
Delivery Time: within 3 days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 500kgs/week
Detailed Product Description
Name: Linagliptin Cas: 668270-12-0
Mf: C25h28n8o2 Purity: 99%
Appearance: White Powder Package: 1kg/bag Or 25kgs/drum
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Linagliptin Active Pharmaceutical Ingredient


668270-12-0 Linagliptin Api Chemical


c25h28n8o2 Linagliptin Api Chemical


Linagliptin Manufacturers Supply High Quality Linagliptin Raw with Best Price CAS  668270-12-0  Linagliptin



Product name Linagliptin
CAS 668270-12-0
Appearance white powder
Assay 99%
Storage Cool and Protect from light

Product Name:Linagliptin
Mol File:668270-12-0.mol
Melting point:202 ºC
Boiling point:661.2±65.0 °C(Predicted)
Density 1.39



Linagliptin (TrajentaR, TradjentaTM, TrazentaTM, TrayentaTM) is an oral, highly selective inhibitor of dipeptidyl peptidase-4 and is the first agent of its class to be eliminated predominantly via a nonrenal route. Linagliptin is indicated for once daily use for the treatment of adults with type 2 diabetes mellitus.
Treatment of Type 2 diabetesLinagliptin acts to lower blood glucose levels by inhibiting the enzyme DPP-4, thereby preventing the degradation of the incretin hormones (glucagon-like peptide-1 [GLP-1] and glucose-dependent insulinsotropic peptide) and attenuating postprandial glucose excursions. By selectively targeting DPP-4, linagliptin potentially causes a more physiologically based control of glucose-dependent postprandial glucose excursions and of fasting blood glucose, both of which are mediated by effects of glucose on insuline and glucagon secretion. An advantage of linagliptin is that since incretin-stimulated release of insuline is glucose dependent, linagliptin is associated with a low incidence of hypoglycaemia. Moreover, DPP-4 inhibitors have a low potential for drug-drug interactions (with the exception of saxagliptin, which is metabolized by cytochrome P450 [CYP] 3A4/5), are generally well tolerated and have minimal or neutral effects on bodyweight. 
PharmacokineticsLinagliptin shows modest oral bioavailability, and it is rapidly absorbed. UsesA novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes.
Usesdipeptidypeptidase inhibitor, antidiabetic
Useshighly potent CD26 inhibitor

UsesLabeled Linagliptin, intended for use as an internal standard for the quantification of Linagliptin by GC- or LC-mass spectrometry.



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