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Api Terbinafine Hydrochloride CAS 78628-80-5 For Antifungals

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Api Terbinafine Hydrochloride CAS 78628-80-5 For Antifungals

Api Terbinafine Hydrochloride CAS 78628-80-5 For Antifungals
Api Terbinafine Hydrochloride CAS 78628-80-5 For Antifungals

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Product Details:
Place of Origin: China
Brand Name: germax
Certification: GMP
Model Number: Terbinafine Hydrochloride
Payment & Shipping Terms:
Minimum Order Quantity: 100 grams
Price: Negotiable
Packaging Details: 1kg/bag or 25kgs/drum
Delivery Time: within 3 days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 500kgs/week
Detailed Product Description
Name: Terbinafine Hydrochloride Cas: 78628-80-5
Appearance: White Powder Purity: 99%
Package: 1kg/carton; 25kg/drum Standard: USP/EP/CP/BP
Storage: Keep In Dark And Dry Place MF: C21H26ClN
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Terbinafine Hydrochloride

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Antifungals Terbinafine Hydrochloride

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78628-80-5 Terbinafine Hydrochloride

Terbinafine Hydrochloride CAS 78628-80-5 for Antifungals Terbinafine HCl Powder

 

 

Terbinafine·HCl a member of the allylamine class of antifungals, has been found to be a specific inhibitor of ergosterol synthesis via squalene epoxidase inhibition. Squalene epoxidase is an enzyme released by the dermatophyte fungi to break down Squalene,which interferes with cell membrane function and wall synthesis. Research has shown that Terbinafine also reduces the ability of fungal pathogens to generate reactive oxygen species, therefore it is noted as a free radical scavenger in vitro and could potentially contain anti-inflammatory activity in vivo.

Product Name
Terbinafine hydrochloride
Specification
99%
Appearance
White powder
Quality Standard
CP2010, USP29
CAS NO.
78628-80-5
Molecular formula
C21H26ClN
Molecular Weight
327.89
 
Terbinafine hydrochloride is an allylamine broad-spectrum antifungal drug. Its mechanism of action is that it can specifically interfere with the early biosynthesis of fungal sterol, and highly selectively inhibit the ergostene cyclooxygenase of fungi. During the formation of fungal cell membrane, the epoxidation reaction of ergosterol is blocked, which interferes with the early biosynthesis of ergosterol in fungi, so as to kill or inhibit fungi Use.
 
Terbinafine hydrochloride is a white crystalline powder; it is easily soluble in methanol, soluble in ethanol or chloroform, slightly soluble in propylene glycol and slightly soluble in water. Terbinafine hydrochloride is widely used in the treatment of various skin fungal infections (tinea pedis, tinea cruris and tinea corporis), Candida (such as Candida albicans) and nail fungal infections. It has a wide range of applications, good efficacy, good tolerance and mild adverse reactions; 
 
Clinical comparative studies showed that skin antifungal agents were significantly better than miconazole nitrate, ketoconazole, itraconazole, fluconazole, griseofulvin, etc. topical or oral administration should be considered according to the site, severity, scope and completeness of the infection.
 

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