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CAS 318-98-9 Synthetic Research Chemicals Pranolol Hydrochloride

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CAS 318-98-9 Synthetic Research Chemicals Pranolol Hydrochloride

CAS 318-98-9 Synthetic Research Chemicals Pranolol Hydrochloride
CAS 318-98-9 Synthetic Research Chemicals Pranolol Hydrochloride

Large Image :  CAS 318-98-9 Synthetic Research Chemicals Pranolol Hydrochloride Get Best Price

Product Details:
Place of Origin: China
Brand Name: germax
Certification: GMP
Model Number: Pranolol Hydrochloride
Payment & Shipping Terms:
Minimum Order Quantity: 100 grams
Price: Negotiable
Packaging Details: 1kg/bag or 25kgs/drum
Delivery Time: within 3 days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 500kgs/week
Detailed Product Description
Name: Pranolol Hydrochloride Cas: 318-98-9
Appearance: White Powder Purity: 99%
Package: 1kg/carton; 25kg/drum Standard: USP/EP/CP/BP
Storage: Keep In Dark And Dry Place MF: C16H22ClNO2
High Light:

Pranolol Hydrochloride Research Chemicals

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CAS 318-98-9 Synthetic Research Chemicals

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C16H22ClNO2 Synthetic Research Chemicals

Pharmaceutical Raw Materials High Purity 99% CAS 318-98-9 PRO Pranolol Hydrochloride

 

 

Products Description

Product Name:propranolo hydrochloride
Synonyms:(RS)-1-[(1-METHYLETHYL)AMINO]-3-(1-NAPHTHALENYLOXY)-2-PROPANOL HYDROCHLORIDE;PROPRANOLO HCL;(+/-)-PROPRANOLO HYDROCHLORIDE;PROPRANOLO HYDROCHLORIDE;(+/-)-PROPANOLOL HCL;PROPANOLOL HYDROCHLORIDE;1-((1-methylethyl)amino)-3-(1-naphthalenyloxy)-2-propanohydrochloride;1-(1-naphthyloxy)-2-hydroxy-3-isopropylaminopropanehydrochloride
CAS:318-98-9
MF:C16H22ClNO2
MW:295.8
EINECS:206-268-7
Product Categories:Aromatic alcohols and diols;Intermediates & Fine Chemicals; Pharmaceuticals; API's; APIs; Amines; Aromatics;Pharmaceutical intermediate;INDERAL
Melting point:163-165 °C(lit.)
Fp:9ºC
storage temp.:2-8°C
solubility:H2O: 50 mg/mL, clear, colorless
Chemical Properties:Off-White to Light-Yellow Cyrstalline Solid
Uses:Adrenergic blocker. Antihypertensive; antianginal; antiarrhythmic (class II).
Uses:For the prophylaxis of migraine


Propranolo is a nonselective beta-adrenergic receptor blocking agent possessing no other autonomic nervous system activity. It specifically competes with beta-adrenergic receptor stimulating agents for available receptor sites. When access to beta-receptor sites is blocked by propranolo, chronotropic, inotropic, and vasodilator responses to beta-adrenergic stimulation are decreased proportionately.
Propranol hydrochloride is an oral drug that can reduce the burden on your heart and help it beat it more effectively. It is used to treat high blood pressure, control rhythm, relieve chest pain, prevent migraine, reduce tremor or tremor, and help thyroid and adrenal gland conditions.
The drug has a different dosage form, including oral tablets, extended release capsules and liquid solutions.
Your dose depends on the form of the drug you are taking, the condition being treated, your age and your response to the drug. Your doctor will decide to fit your dose.
Common side effects include sexual behavior or performance changes, diarrhea, dry eyes, hair loss, nausea, fatigue or fatigue.
Do not stop taking this medicine unless your doctor tells you. Sudden cessation of propranolo can worsen your heart disease, especially if you have heart disease. If necessary, your doctor will tell you how to safely stop.

 

 

Use:

This medication is a beta blocker used to treat high blood pressure, irregular heartbeats, shaking (tremors), and other conditions. It is used after a heart attack to improve the chance of survival. It is also used to prevent migraine headaches and chest pain (angina). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Preventing chest pain can help improve your ability to exercise.

This drug works by blocking the action of certain natural chemicals in your body (such as epinephrine) that affect the heart and blood vessels. This effect reduces heart rate, blood pressure, and strain on the heart.

Specification

Items Specifications Results
Appearance A white or almost white powder Conforms
Solubility Soluble in water and in ethanol (96%) Conforms
Identification  
A Melting point : 163°C~166°C 164.0~164.5°C
B Examine by infrared absorption spectrophotometry, comparing with the spectrum obtained with propranolo hydrochloride CRS. Conforms
C Examine by thin-layer chromatography. The principal spot in the chromatogram obtained with the test solution is similar in position, colour and size to the principal spot in the chromatogram obtained with the reference solution. Conforms
D It gives reaction(a) of chlorides Conforms
Tests  
Appearance of solution The solution is clear and not more intensely coloured than intensity 6 of the range of reference solutions of the most appropriate colour Conforms
Acidity or alkalinity Add 0.1ml of methyl red solution R and 0.2 ml of 0.01M hydrochloric acid, the solution is red. Add 0.4ml of 0.01 M sodium hydroxide. The solution is yellow. Conforms
Related substances Any impurity NMT 0.1% 0.03%
  The sum of all impurities NMT 0.4% 0.21%
Heavy metals NMT 20ppm Conforms
Loss on drying NMT 0.5% 0.11%
Sulphated ash NMT 0.1% 0.08%
Residual solvents A: ethanol: NMT 5000ppm
B: Xylene: NMT 2170ppm
Conforms
Conforms
Assay 99.0%~101.0% 99.3%
Conclusion: conform to EP7.0

 

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