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Pancreatic Lipase Inhibitor Cetilistat Powder CAS 282526-98-1

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Pancreatic Lipase Inhibitor Cetilistat Powder CAS 282526-98-1

Pancreatic Lipase Inhibitor Cetilistat Powder CAS 282526-98-1
Pancreatic Lipase Inhibitor Cetilistat Powder CAS 282526-98-1

Large Image :  Pancreatic Lipase Inhibitor Cetilistat Powder CAS 282526-98-1 Get Best Price

Product Details:
Place of Origin: China
Brand Name: germax
Model Number: Raw Steroid Powder
Payment & Shipping Terms:
Minimum Order Quantity: 1kg
Price: Negotiable
Packaging Details: 1kg/bag or 25kgs/drum
Delivery Time: within 3 days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 2000kgs/month
Detailed Product Description
Name: Cetilistat CAS: 282526-98-1
Purity: 99.5% Appearance: White Powder
Packing: 1kg/Bag,10kg/Drum,25kg/Drum Or As Required MF: C25H39NO3
High Light:

Cetilistat Powder


CAS 282526-98-1


Cetilistat Synthetic Research Chemicals

Good Quality Novel Pancreatic Lipase Inhibitor Cetilistat CAS 282526-98-1 Cetilstat

Product Name: Cetilistat
Synonyms: cetilistat;Cetilistat(Alt-962);Cetilstat;2-(Hexadecyloxy)-6-methyl-4H-3,1-benzoxazin-4-one;2-(Hexadecycloxy)-6-methyl-4H-3,1-benzoxazin-4-one;New alistat;2-hexadecoxy-6-methyl-3,1-benzoxazin-4-one;Cetilistat (ATL-962)
CAS: 282526-98-1
MF: C25H39NO3
MW: 401.58
EINECS: 621-260-7

Melting point: 72.0 to 76.0 °C
Boiling point: 509.7±43.0 °C
Density: 1.02
Storage temp.: Store at RT
Appearance: Off-white Powder


Cetilistat (also known as ATL-962) was approved in September 2013 by the Japanese Ministry of Health, Labor and Welfare for the treatment of obesity, limited to patients with both type 2 diabetes mellitus (T2DM) and dyslipidemia, and with a body mass index (BMI)25 kg/m2 in spite of dietary treatment and/or exercise therapy. As with orlistat, cetilistat works via inhibition of pancreatic lipases in the gut to inhibit fat absorption and thereby reduce caloric uptake from diet. The medicinal chemistry program has not been described in the scientific literature, but the patent describing cetilistat also describes the synthesis of analogs with varied aryl substituents and lipophilic tails. The synthesis of cetilistat involves condensation of a hexadecylcarbonochloridate with 2-amino-5-methylbenzoic acid; other analogs were synthesized by varying the carbonochloridate and 2-aminobenzoic acid components. Cetilistat is a potent inhibitor of human and rat pancreatic lipase with IC50s of 15 and 136 nM, respectively, with little inhibition of trypsin or chymotrypsin.


A novel pancreatic lipase inhibitor for the treatment of obesity in both diabetic and non-diabetic patients.


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