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Autoimmune Diseases Tacrolimus Powder CAS 104987-11-3

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Autoimmune Diseases Tacrolimus Powder CAS 104987-11-3

Autoimmune Diseases Tacrolimus Powder CAS 104987-11-3
Autoimmune Diseases Tacrolimus Powder CAS 104987-11-3

Large Image :  Autoimmune Diseases Tacrolimus Powder CAS 104987-11-3 Get Best Price

Product Details:
Place of Origin: China
Brand Name: germax
Model Number: Tacrolimus
Payment & Shipping Terms:
Minimum Order Quantity: 10 gram
Price: Negotiable
Packaging Details: 10g/bottle ,50g/bottle , 100g/bag ,1kg/bag
Delivery Time: within 3 days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 2000 grams/month
Detailed Product Description
Name: Tacrolimus CAS: 104987-11-3
Purity: 99.5% MF: C44H69NO12
Appearance: White Powder Packing: 1kg/Bag,10kg/Drum,25kg/Drum Or As Required
High Light:

Autoimmune Diseases Tacrolimus Powder


CAS 104987-11-3 Tacrolimus Powder


C44H69NO12 Tacrolimus Powder

Fk506 Good for Autoimmune Diseases Tacrolimus CAS: 104987-11-3 Fast Delivery



Product Name Tacrolimus
Alias Tsukubaenolide Hydrate
CAS 109581-93-3
MF C44H69NO12
MW 804.02
Grade Pharmaceutical Grade
Appearance White To Light Yellow Crystal Powder


Tacrolimus is an immunosuppressive drug used mainly after allogeneic organ transplant to lower the risk of organ rejection. It achieves this by inhibiting the production of interleukin-2, a molecule that promotes the development and proliferation of T cells, which are vital to the body's learned (or adaptive) immune response. Tacrolimus is also used in the treatment of other T cell-mediated diseases such as eczema (for which it is applied to the skin in a medicated ointment), severe refractory uveitis after bone marrow transplants, exacerbations of minimal change disease, Kimura's disease and the skin condition vitiligo.


Test:CAS: 104987-11-3 Tacrolimus

Appearance White powder Complies
Assay (HPLC) ≥98% 98.5%
Sieve analysis NLT 95% pass 80 mesh Complies
Loss on Drying ≤2.0% 1.95%
Ash ≤5.0% 2.15%
Pb <2ppm Complies
As <2ppm Complies
Hg <2ppm Complies


Tacrolimus (also FK-506 or Fujimycin) is an immunosuppressive drug.It was discovered in 1984 from the fermentation broth of a Japanese soil sample that contained the bacteria Streptomyces tsukubaensis. Tacrolimus is chemically known as a macrolide. It reduces peptidyl-prolyl isomerase activity by binding to the immunophilin FKBP-12 (FK506 binding protein) creating a new complex. This FKBP12-FK506 complex interacts with and inhibits calcineurin thus inhibiting both T-lymphocyte signal transduction and IL-2 transcription.


Function and Application of Tacrolimus
1. Tacrolimus is used with other medications to prevent rejection of a kidney, heart, or liver transplant.
2. Tacrolimus is also used in a topical preparation in the treatment of severe atopic dermatitis, severe refractory uveitis after bone marrow transplants, and the skin condition vitiligo.
3. Tacrolimus can be combined with steroids, azathioprine (Imuran Azasan) or mycophenolate mofetil (CellCept



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