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Rapamycin Fine Research Chemicals Sirolimus 99.5% CAS 53123-88-9

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Rapamycin Fine Research Chemicals Sirolimus 99.5% CAS 53123-88-9

Rapamycin Fine Research Chemicals Sirolimus 99.5% CAS 53123-88-9
Rapamycin Fine Research Chemicals Sirolimus 99.5% CAS 53123-88-9

Large Image :  Rapamycin Fine Research Chemicals Sirolimus 99.5% CAS 53123-88-9 Get Best Price

Product Details:
Place of Origin: China
Brand Name: germax
Model Number: Rapamycin
Payment & Shipping Terms:
Minimum Order Quantity: 10 gram
Price: Negotiable
Packaging Details: 10g/bottle ,50g/bottle , 100g/bag ,1kg/bag
Delivery Time: within 3 days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 2000 grams/month
Detailed Product Description
Name: Rapamycin CAS: 53123-88-9
Purity: 99.5% MF: C51H79NO13
Appearance: White Powder Packing: 1kg/Bag,10kg/Drum,25kg/Drum Or As Required
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Rapamycin Fine Research Chemicals


Sirolimus 99.5% Fine Research Chemicals


CAS 53123-88-9

High Purity Rapamycin white powder Sirolimus 99.5%Min CAS 53123-88-9 with Best Price










Melting point:183-185°C

alpha D25 -58.2° (methanol)

Flash point:87 °C

storage temp. -20°C

solubility ethanol: soluble2MM

color colorless to yellow

Water Solubility Soluble in DMSO at 50mg/ml or methanol at 25mg/mlSoluble in alcohol, dimethyl sulfoxide and dimethylformamide. Insoluble in water.

Sensitive Moisture Sensitive/Light Sensitive/Hygroscopic


Item Specifications Results
Description off-white to yellow crystalline powder Complies

The IR spectrum of Potassium Bromide preparation of the sample exhibits maxima at the same wavelengths as that of a similar preparation of in-house reference standard Complies
The UV spectrum of 95% Ethanol preparation of the sample exhibits maxima at 267nm,277nm, 288nm that of similar preparation of in-house reference standard. Complies
The retention times of the peaks for the Trans- and Cis-stereoisomers in the chromatogram of Assay preparation corresponds to that in the chromatogram of the standard preparation, as obtained in the Assay Complies
Loss on drying ≤0.5% 0.16%
Heavy metal ≤0.002% Complies
Total impurity ≤2.0% 0.76%
Single impurity ≤1.0% 0.67%
Cis-stereoisomer of Sirolimus ≤5.0% 2.4%
Assay ≥98.0% 99.5%



Sirolimus is indicated for the prevention of organ transplant rejection and for the treatment oflymphangioleiomyomatosis

Rapamycin initially was taken as low toxicity antifungal drugs, and was found immunosuppressive in 1977. From 1989, RAPA was as a new drug for the treatment of organ transplantation rejection in trial, and from animal experiments and clinical application effects, it is of good curative effects, low toxicity and no new immunosuppressant nephrotoxicity.

Now rapamycin is frequently as maintaining immunity drug for transplant organs (especially kidney transplant), to slow down the immune rejection of the organ in transplant surgery, however, scientists recently discovered another purpose: it can be used in the treatment of alzheimer's disease (senile dementia).

Medical researchers from University of Chicago combined commercially available rapamycin oral tablets with grapefruit juice in the treatment of melanoma (a kind of malignant tumor disease common in European and American people), which could greatly improve the anticancer effect of other chemotherapy drugs, thereby prolong the survival time of patients.



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