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| Product Name: | Acetate | CAS No: | 71-58-9 |
|---|---|---|---|
| Apperance: | White Powder | Assay: | 99% |
| MF: | C24H34O4 | Usage: | Pharmaceutical Raw Material |
| Alias: | Acetate Manufacturer | ||
| High Light: | High Purity 99% acetate powder,API Medroxyprogesterone Acetate Powder,CAS 71-58-9 Raw Hormone Powder |
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Basic Information:
Synonyms: (6-alpha)-17-(acetyloxy)-6-methylpreg-4-ene-3,20-dione; 17-(acetyloxy)-6-methyl-(6-alpha)-pregn-4-ene-20-dione; 17-(acetyloxy)-6-methyl-20-dion(6alpha)-pregn-4-ene-; 17-acetoxy-6-alpha-methylprogesterone; 17-alpha-hydroxy-6-alpha-methylpregn-4-ene-3,20-dioneacetate; 17-alpha-hydroxy-6-alpha-methyl-progesteronacetate; 17-alpha-hydroxy-6-alpha-methylprogesteroneacetate; 17-hydroxy-6-alpha-methylpregn-4-ene-3,20-dioneacetate
CAS: 71-58-9
MF: C24H34O4
MW: 386.52
EINECS: 200-757-9
Product Categories: Antitumors for Research and Experimental Use;Biochemistry;Hydroxyketosteroids;Steroids;Intermediates & Fine Chemicals;Pharmaceuticals;Steroid and Hormone;API;PROVERA;Hormone Drugs
Mol File: 71-58-9.mol
Chemical Properties:
MP: 206-207 °C(lit.)
refractive index: 48 ° (C=1, Dioxane)
storage temp.: Refrigerator
Water Solubility: <0.1 g/100 mL at 23 ºC
Merck 13,5817
Appearance: Odorless white to off-white microcrystalline powder.
Stability: Stable, but weakly air and light sensitive. Incompatible with strong oxidizing agents.
Description:
Medroxyprogesterone acetate (INN, USAN, BAN), also known as 17α-hydroxy-6α-methylprogesterone acetate, and commonly abbreviated as MPA, is a steroidal progestin, a synthetic variant of the steroid hormone progesterone. It is used as a contraceptive, in hormone replacement therapy and for the treatment of endometriosis as well as several other indications.
MPA is a more potent derivative of its parent compound medroxyprogesterone (MP). While medroxyprogesterone is sometimes used as a synonym for medroxyprogesterone acetate,what is almost always being referred to is MPA and not MP.It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.
COA:
| ITEMS | SPECIFICATION | RESULTS |
| Character | White or almost white crystalline powder | Almost White crystalline powder |
| Specific optical rotation | +47°to +53° | +48.2° |
| Impurity F | Not more than 0.5% | <0.5% |
| Identification | Complies by IR | Conforms |
| Related substances | Impurity A not more than 0.3% | Undetected |
| Impurity B not more than 0.7% | Undetected | |
| Impurity C not more than 0.2% | Undetected | |
| Impurity D not more than 1.0% | 0.36% | |
| Impurity E not more than 0.2% | Undetected | |
| Impurity G not more than 0.2% | Undetected | |
| Impurity H not more than0.10% | 0.08% | |
| Impurity I not more than 0.2% | Undetected | |
| Unknown impurity not more than 0.10% | 0.05% | |
| Total impurity not more than 1.5% | 0.49% | |
| Loss on drying | Not more than 1.0% | 0.20% |
| Methylene chloride | Not more than 300ppm | 84ppm |
| Methanol | Not more than 2000ppm | 116ppm |
| Assay | Contains 97.0% to 103.0% of C24H34O4 | 99.80% |
| Calculated on dried basis | ||
| Conclusion | The goods conforms to USP | |
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