 |
|
|
|
|
Product Details:
Payment & Shipping Terms:
|
| Product Name: | Clobetasol Propionate | Purity: | 99.5% |
|---|---|---|---|
| Color: | White Powder | Molecular Formula: | C25h32clfo5 |
| Production Capacity: | 500kgs/week | Min Order: | 10g |
| Package: | 1kg/Aluminum Foil Bag Or As Customer Requirement | Storage: | Kept In A Cool,dry And Ventilated Place |
| High Light: | Clobetasol Propionate chemical,25122-46-7 Raw Material USP Grade,C25h32clfo5 white powder |
||
Pharmaceutical raw material USP grade clobetasol propionate powder
Name: Clobetasol propionate
C.A.S NO. : 25122-46-7
Synonyms: 21-Chloro-9-fluoro-11b,17-dihydroxy-16b-methylpregna-1,4-diene-3,20-dione 17-propionate
EINECS NO.: 246-634-3
Molecular formula: C25H32ClFO5
Molecular weight : 466.97
Assay: 99%
Characteristic: White crystalline powder
Clobetasol propionate is a corticosteroid of the glucocorticoid class used to treat various skin disorders including eczema and psoriasis. It is also highly effective for contact dermatitis caused by exposure to poison ivy/oak. Clobetasol belongs to US Class I of the corticosteroids,
making it one of the most potent available. It comes in shampoo, mousse, ointment and emollient cream presentations. It has very high potency and typically should not be used with occlusive dressings, or for extended continuous use (beyond two weeks). It is also used to treat several autoimmune diseases including alopecia areata, lichen sclerosus, and lichen planus.
|
Item
|
Specification
|
Results
|
|
Appearance
|
white to cream,crystalline powder
|
White crystalline powder
|
|
Identification (by IR)
|
Confirms to the CRS spectrum
|
Confirm
|
|
Melting point
|
Approximately 196ºC
|
196ºC
|
|
Specific rotation
|
+98°~+104°(dried substance)
|
+78.0°
|
|
Loss on drying
|
≤ 2.0%
|
0.2%
|
|
Residue on ignition
|
≤0.1%
|
0.04%
|
|
Heavy metals
|
≤20ppm
|
Confirm
|
|
Related substances(by HPLC)
|
Any impurity≤1.0%
Total impurities≤2.5% |
0.15%
0.15% |
|
Assay(by HPLC)
|
Contains 97.0% to 102.0% of C25H32ClFO5
Calculated on dried basis |
100.4%
|
|
Residual solvents
|
Ethanol ≤ 3000ppm
Acetone ≤ 500ppm Pyridine ≤ 100ppm N,N-Dimethylformamide ≤ 100ppm |
269ppm
<4ppm <3ppm <10ppm |
Contact Person: July
Tel: 25838890
