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Terbinafine Hydrochloride Powder CAS 78628-80-5 Terbinafine HCl API

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Terbinafine Hydrochloride Powder CAS 78628-80-5 Terbinafine HCl API

Terbinafine Hydrochloride Powder CAS 78628-80-5 Terbinafine HCl API
Terbinafine Hydrochloride Powder CAS 78628-80-5 Terbinafine HCl API

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Product Details:
Place of Origin: China
Brand Name: germex
Certification: GMP
Model Number: Terbinafine Hydrochloride
Payment & Shipping Terms:
Minimum Order Quantity: 10 gram
Price: Negotiable
Packaging Details: 1kg/bag or 25kgs/drum
Delivery Time: within 24 hours after get the payment
Payment Terms: Western Union, MoneyGram, T/T
Supply Ability: 500KG/week
Detailed Product Description
Product Name: Terbinafine Hydrochloride Appearance: White Powder
Shipment: UPS / DHL / FEDEX / EMS And Client's Request Production Capacity: 500 Kilogram/month
Purity: 99.5% Package: 1kg/Aluminum Foil Bag Or As Customer Requirement
Storage: Kept In A Cool,dry And Ventilated Place
High Light:

Terbinafine Hydrochloride fine chemical


Terbinafine HCl purity 99% API


78628-80-5 Good Chemicals

Terbinafine Hydrochloride Powder CAS 78628-80-5 Terbinafine HCl API


Product Description

Terbinafine hydrochloride is an antifungal, which is highly hydrophobic and tends to accumulate in hair, skin, nails, and fatty tissue.

Terbinafine hydrochloride is a white fine crystalline powder that is freely soluble in methanol and dichloromethane, soluble in ethanol, and slightly soluble in water.

Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting squalene epoxidase, an enzyme that is part of the fungal cell membrane synthesis pathway. Because terbinafine prevents conversion of squalene to lanosterol, ergosterol cannot be synthesize.


Appearance White or almost white powder White powder
Solubility Practically insoluble in water and in aceton, soluble in ethanol and in methanol Complies
A: IR The infrared absorption spectrum exhibits maximum only at the same wavelengths as that of the standard sample Complies














It gives reaction of chlorides Complies
Impurity A NMT 0.1% 0.00%
Impurity B NMT 0.1% 0.01%
Impurity C NMT 0.1% 0.02%
Impurity D NMT 0.1% 0.02%
Any other impurity NMT0.1% 0.05%
Total of impurity NMT 0.3% 0.15%
Loss on drying NMT0.5% 0.15%
Sulphated ash NMT0.1% 0.02%
Assay 99%~101% (dried substance ) 99.85%


1. Terbinafine is mainly effective on the dermatophyte group of fungi.

2. As a 1% cream or powder, it is used topically for superficial skin infections such as jock itch (tinea cruris), athlete's foot (tinea pedis), and other types of ringworm (tinea corporis). Terbinafine cream works in about half the time required by other antifungals.

3. Oral 250-mg tablets are often prescribed for the treatment of onychomycosis, a fungal nail infection, typically by a dermatophyte or Candida species. Fungal nail infections are located deep under the nail in the cuticle to which topically applied treatments are unable to penetrate in sufficient amounts. The tablets may, rarely, cause hepatotoxicity, so patients are warned of this and may be monitored with liver function tests. Alternatives to oral administration have been studied.

4. Terbinafine hydrochloride may induce or exacerbate subacute cutaneous lupus erythematosus. Persons with lupus erythematosus should first discuss possible risks with their doctor before initiation of therapy.

Packaging & Shipping

1kg with double plastic container inside/Aluminum foil bag ;
25kg with double plastic container inside/Fiber drum outside.Or as your request.
Shipped in 3 days after payment.

1.Stored in a cool and dry well-closed container and in ventilated area.
2.kept away from moisture and strong light or high temperature.
3.Two years under well storage situation and stored away from direct sun light.


Contact Details
Germax Pharm Chemicals Co., Ltd

Contact Person: July

Tel: 25838890

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