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Pharmaceutical Raw Material CAS 151767-02-1 Montelukast Sodium Powder

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Pharmaceutical Raw Material CAS 151767-02-1 Montelukast Sodium Powder

Pharmaceutical Raw Material CAS 151767-02-1 Montelukast Sodium Powder
Pharmaceutical Raw Material CAS 151767-02-1 Montelukast Sodium Powder

Large Image :  Pharmaceutical Raw Material CAS 151767-02-1 Montelukast Sodium Powder Get Best Price

Product Details:
Place of Origin: China
Brand Name: germax
Certification: GMP
Model Number: Montelukast Sodium
Payment & Shipping Terms:
Minimum Order Quantity: 10g
Price: Negotiable
Packaging Details: 1kg/bag or 25kgs/drum
Delivery Time: in stock within 24 hours
Payment Terms: Western Union, MoneyGram, T/T, L/C
Supply Ability: 1500kgs/month
Detailed Product Description
Name: Montelukast Sodium Appearance: White/yellow Powder
Production Capacity: 1500kgs/month Application: API
Purity: 99% CAS No.: 151767-02-1
Molecular Formula: C35h35clnnao3s
High Light:

Montelukast Sodium Raw Material


CAS 151767-02-1 Powder


C35h35clnnao3s Research Chemicals

Montelukast Sodium is a potent, selective, anti-inflammatory CysLT1 receptor antagonist (IC50 < 5nM) with no appreciable affecton the CysLT2 receptor. In rat colitis Montelukast Sodium has demonstrated the ability to increase PGE2 (Prostaglandin E2 - sc-201225) production and lower COX-2 expression. Inhibition is competitive with respect to leukotrienes - particularly LTD4, a biologically active mediator that plays an important role in the control of several biochemical pathways involving pulmonary and immune system function.Because of its method of operation, it is not useful for the treatment of acute asthma attacks. Again because of its very specific mechanism of action, it does not interact with other asthma medications such as theophylline.Another leukotriene receptor antagonist is zafirlukast (Accolate), taken twice daily. Zileuton (Zyflo), an asthma drug taken four times per day, blocks leukotriene synthesis by inhibiting 5-lipoxygenase, an enzyme of the eicosanoid synthesis pathway.



Product name
Montelukast Sodium
White powder
Shelf life
2 years
Stored in a well-closed container at low temperature, keep away from moisture, heat and light.

Certificate of Analysis

Function & Application:

Montelukastis a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies.Montelukast comes as a tablet, a chewable tablet, flash tablet and granules to take by mouth.Montelukast is usually taken once a day with or without food.Montelukast is a CysLT1 antagonist; it blocks the action of leukotriene D4 (and secondary ligands LTC4 and LTE4) on the cysteinyl leukotriene receptor CysLT1 in the lungs and bronchial tubes by binding to it. This reduces the bronchoconstriction otherwise caused by the leukotriene and results in less inflammation.

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