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Product Details:
Payment & Shipping Terms:
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Name: | Heparin Sodium | CAS No.: | 9041-08-1 |
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Form: | White Crystalline Powder | Content: | 99% |
Min Order: | 10g | Package: | 1kg/bag Or 25kgs/drum |
High Light: | Heparin Sodium chemical product,9041-08-1 GMP for Preventing Thrombosis,(C12H16NS2Na3)20 white powder |
Product Name | HEPARIN SODIUM |
Appearance | White to off- white powder |
Residue on ignition | 28.0%- 41.0% |
Nitrogen(calculated on the dried basis ) | 1.3%-2.5% |
Heavy metals | ≤30ppm |
Limit of galactosamine in total hexosamine | ≤1% |
Nucleotidic impurities | Absorbance at 260nm: ≤0.20 |
Absence of oversulfated chondroitin sulfate |
A. Proceed as directed in identification test A. No features associated with oversulfated chondroitin sulfate are found between 2.12 and 3.00ppm B. No peaks corresponding to oversulfated chondroitin sulfate should be detected eluting after the heparin peak. |
PH | 5.0-7.5 |
Loss on drying | ≤5.0% |
Protein impurities | ≤1.0% |
Bacterial endotoxins test | Not more than 0.03 USPEU/USPU of Heparin |
Not more than 0.03 USPEU/USPU of Heparin | ≥180 IU/mg |
Residual solvents | Ethanol: ≤ 5000 ppm |
Microbial contamination | A:Total viable aerobic count: max 10CFU/g B: Molds/yeasts |
Function & Application:
(1)Heparin sodium is white or white powder, tasteless, hygroscopic, soluble in water, insoluble in ethanol, acetone and other organic solvents. It has a strong negative charge in aqueous solution and can combine with some cations to form molecular complexes. The aqueous solution is stable at a pH of 7.
(2) Heparin sodium interferes with many of the steps of blood coagulation, and has anticoagulant effects in and out of the body. Its mechanism is complex, mainly through and antithrombin III (AT - III), and enhance the latter to activate II, IX, X, XI and XII the inhibitory effect of clotting factors and its consequences involved in preventing platelet aggregation and destruction, inhibit the formation of blood coagulation activation of enzyme, blocking prothrombin into thrombin, inhibition of thrombin, thereby preventing fibrinogen to fibrin, which play a role of anticoagulation.
Contact Person: July
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