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Product Details:
Payment & Shipping Terms:
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Purity: | 99.5% | Appearance: | White Powder |
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Application: | Research Chemical | Package: | Aluminum Foil Bag |
Port: | Beijing, Shenzhen, Tianjin, HK | Storage: | Kept In A Cool |
High Light: | Research Chemicals Intermediates,Clobetasol Propionate,Raw Material CAS 25122-46-7 |
High Quality Pharmaceutical Raw Material CAS 25122-46-7 Clobetasol Propionate
Name | Clobetasol Propionate |
CAS NO. | 25122-46-7 |
Molecular formula | C25H32ClFO5 |
Assay | 99% |
Characteristic | White crystalline powder |
Molecular weight | 466.97 |
Certificate of Analysis
Test items
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Standard
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Result
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Description
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White to off- White powder
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Conforms
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Identification
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IR spectrum of sample is the same as working standard
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Conforms
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HPLC RT of the sample is the same as the working standard
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Conforms
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Melting point
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165.0°C~169.0°C
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165.8°C~167.0°C
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Optical rotation
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-23°~-29°
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-27.4°
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Loss on drying
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NMT 1.0 %
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0.0017
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Residue on ignition
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NMT 0.1 %
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0.0003
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Heavy metals
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NMT 20ppm
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Conforms
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Related substances
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Impurity A
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NMT 0.1 %
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Not detected
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Impurity B
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NMT 0.1 %
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Not detected
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Impurity C
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NMT 0.1 %
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0.0002
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Single impurity
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NMT 0.2 %
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0.0017
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Total impurity
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NMT 1.0 %
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0.006
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Assay
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NLT 99.0%
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0.99
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Function & Application
1. Anti-inflammatory effects: The product can reduce and prevent tissue response to inflammation, thereby reducing inflammation performance. Hormone suppression of inflammatory cells, including leukocytes and macrophages accumulation in sites of inflammation and inhibition of phagocytosis, lysosomal enzyme release and synthesis and release of inflammatory chemical mediators. Can reduce and prevent tissue response to inflammation, thereby reducing inflammation performance.
2. Immunosuppressive effect: preventing or inhibiting cell-mediated immune response, delayed hypersensitivity reactions, reducing T lymphocytes, monocytes, eosinophils, reducing immunoglobulin binding to cell surface receptors and inhibition of the synthesis and release of interleukin, thus reducing the T lymphocyte transformation of lymphoblastoid cells, and reduce the extension of the primary immune response. Can reduce immune complexes through the basement membrane, and can reduce the concentration of ingredients complement and immunoglobulins.
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